Benadering van enkele klassieke filosofische kwesties vanuit een door de Angelsaksische taalfilosofie geïnspireerde visie op de zingevende rede.

Donors to biobanks are typically asked to give blanket consent, allowing their donation to be used in any research authorized by the biobank. This type of consent ignores the evidence that some donors have moral, religious, or cultural concerns about the future uses of their donations – concerns we call “non-welfare interests”. The nature of non-welfare interests and their effect on willingness to donate to a biobank is not well understood. In order to better undersand the influence of non-welfare interests, (...) we surveyed a national sample of the US population using a probability-based internet panel. Logistic regression models assessed the demographic and attitudinal characteristics associated with participants’ willingness to give consent for unspecified future uses of their donation when presented with 7 research scenarios that raised possible non-welfare interest concerns. Most people had non-welfare interests that significantly affect their willingness to donate to a biobank using blanket consent. Some non-welfare interests are associated with subgroups but others are not. A positive attitude toward biomedical research in general was associated with increased willingness to donate, while concerns about privacy and being African American were associated with decreased willingness. Non-welfare interests matter and can diminish willingness to donate to a biobank. Our data suggest that trust in research promotes willingness to donate. Ignoring non-welfare interests could erode this trust. Donors’ non-welfare interests could be accommodated through greater transparency and easier access to information about the uses of donations. (shrink)

Drawing its strength from the UN Charter and UDHR, human rights ethics is a beacon of hope and a promise that requires continuous reaffirmation during these turbulent times. These two documents, with their unwavering faith in ‘fundamental human rights, in the dignity and worth of the human person, in the equal rights of men and women and of nations large and small,’ have shaped our understanding of human rights as global and universal ethics. However, this faith is now being severely (...) tested by four countercurrents: extremism, exclusionism, selectivism, and populism. These countercurrents pose significant and urgent human rights threats that activists, academics, and policymakers must confront by reasserting the basic core values of the UN Charter and UDHR. (shrink)

En el socialismo de la transición, De los Ríos fue una figura a recuperar. Su sentido humanista del socialismo permitió al PSOE fundar en su propia historia republicana el nuevo compromiso del socialismo con la libertad. En el socialismo de los derechos civiles también tiene un lugar. De los Ríos apadrinó a Federico García Lorca, desde Granada a Nueva York y con La Barraca. El amor y el exilio acabó uniendo sus familias. También nombra a la primera mujer alto cargo (...) gubernamental: Victoria Kent, directora de prisiones.Se conoce menos otra dimensión de su trayectoria política de la que se ocupa este libro: su laicismo religioso. Dos rasgos que en la España de duelos a garrotazos parecen antagónicos. Sin embargo, ambos son característicos de su personalidad política e intelectual. Fue el ministro que lideró la política laicizadora de la II República, desde Justicia, primero, e Instrucción pública, después, llevando "siempre la batuta"?como informaba Tedeschini, el nuncio de la época -. Por otra parte, desde un cristianismo heterodoxo, no dejó de estimar la emoción religiosa, como lugar donde "fecundan los más hondos deseos del ideal". Se autodefinió "cristiano erasmista". Así le caracterizan Indalecio Prieto, en el obituario tras su muerte en el exilio, y el propio García Lorca, su poeta. (shrink)

Neste artigo, busco elucidar a noção de política segundo Hannah Arendt a partir de um questionamento proveniente da sociologia de Ulrich Beck. Na medida que H. Arendt pensa a política como uma condição dependente da continuidade material assegurada por um mundo artificialmente construído, e U. Beck identifica na modernidade de risco o surgimento de uma série de instabilidades naturais socialmente iniciadas, pergunto em que medida tal transformação do mundo humano afeta a política tal como foi pensada pela autora. A partir (...) disso, reconstruo a leitura de H. Arendt acerca da relação da política com a condição humana, buscando elucidar tanto o sentido ético da política enquanto atividade reguladora de nossa liberdade (como visualizado pela autora), quanto o que significa pensar o ser humano como um animal livre e condicionado ao mesmo tempo. (shrink)

Pero queda, a través de este devenir, la luz mosaica, las Tablas de la Ley, las sentencias del Talmud, las profecías de la Biblia. Este es el Tesoro del pueblo Judaico, el único que se ha conservado a través de los siglos; el que todavía suena en los momentos de la mayor angustia para la Humanidad y que vése conmovido por el impetuoso torrente de la vida contemporánea que exige nueva vitalidad en todos los aspectos de la existencia humana. DR. (...) ADALBERTO GARCÍA DE MENDOZA. (shrink)

The authors explore whether the need for ethical reflection on the part of designing engineers is dependent on the type of design process. They use Vincenti's distinction between normal and radical design and different levels of design hierarchy. These two dimensions are coupled with the concept of ill-structured problems, which are problems in which possible solutions cannot be ordered on a scale from better to worse. Design problems are better structured at lower hierarchical levels and in cases of normal design. (...) Better structured design problems require less ethical reflection on the part of designing engineers if such situations are characterized by the existence of generally accepted normative frameworks. Engineers could then deal with moral problems within the bounds of such frameworks and without the need for further reflection. On the basis of a number of empirical cases, the authors explore whether these ideas hold water. They discuss four cases ranging from a high-level radical design process to a low-level normal design process. (shrink)

Oproep aan christenen om zich te bezinnen en terug te keren tot het wezenlijke van hun geloof.

Las siguientes páginas versan sobre la idea del Estado en la obra de José Ortega y Gasset, mostrando los cambios que en torno a aquella idea se producen en su pensamiento. En un primer periodo de mocedad, Ortega idealiza el papel de Estado influido por la tradición del pensamiento clásico y germano. En un segundo momento, a partir de la programática fecha de 1914, se producirá un giro en su pensamiento, quedando el Estado al servicio de la sociedad o la (...) realidad nacional, y por lo tanto en una posición “subalterna” frente a la posición dominante que Ortega le concedía en sus primeros años como intelectual. (shrink)

The enormous destructive power of present stocks of nuclear weapons poses the greatest threat to public health in human history. Technical changes in weapons design are leading to an increased emphasis on the ability to fight a nuclear war, eroding the concept of deterrence based on mutually assured destruction and increasing the risk of nuclear war. Medical planning and civil defence preparations for nuclear war have recently been increased in several countries although there is little evidence that they will be (...) of significant value in the aftermath of a nuclear conflict. These developments have raised new ethical dilemmas for those in health professions. If there is any risk of use of weapons of mass destruction, then support for deterrence with these weapons as a policy for national or global security appears to be incompatible with basic principles of medical ethics and international law. The primary medical responsibility under such circumstances is to participate in attempts to prevent nuclear war. (shrink)

v. 1. Bibliographia historiæ philosophiæ.--v. 2. Bibliographia philosophiæ.

Resumo Neste artigo, será discutida a noção de “infinitude cardinal” – a qual seria predicada de um “conjunto” – e a noção de “infinitude ordinal” – a qual seria predicada de um “processo”. A partir dessa distinção conceitual, será abordado o principal problema desse artigo, i.e., o problema da possibilidade teórica de uma infinitude de estrelas tratado por Dummett em sua obra Elements of Intuitionism. O filósofo inglês sugere que, mesmo diante dessa possibilidade teórica, deveria ser possível predicar apenas infinitude (...) ordinal. A questão principal surge do fato de que parece ser problemático predicar ordinalmente infinitude de “estrelas”. Mesmo diante dessa possibilidade, Dummett sugere que o intuicionista poderia apenas reinterpretar infinitude cardinal como sendo infinitude ordinal. Ora, iremos mostrar que, se Dummett não fornece razões extras que sustentem essa posição, então será difícil interpretar um caso empírico infinitário como sendo também um caso ordinal ou potencial de infinitude. Para resolver esse problema de Dummett, em Brouwer se encontram alguns pressupostos idealistas necessários para argumentar em favor da ideia de que, mesmo em um contexto empírico, como o de uma infinitude de estrelas, poderíamos predicar infinitude ordinal. Então, depois de discutir as duas noções de “infinitude” e apresentar o problema de Dummett, será apresentada a abordagem idealista de Brouwer – a qual pelo menos explicaria de modo mais plausível as razões que poderiam motivar um intuicionista a predicar infinitude ordinal até mesmo de um caso empírico e espacial. (shrink)

Echte Freiheit läßt sich nach Leibniz nicht auf die Möglichkeit reduzieren, so zu handeln, wie man handeln will. Vielmehr muß echte Freiheit mit dem moralischen Verdienst in Verbindung gebracht werden. In diesem Zusammenhang erweist sich die Idee der logischen Kontingenz von besonderer Wichtigkeit. Eine Person hat kein moralisches Verdienst, wenn sie blindlings durch das Gute geleitet wird. Sie hat allein dann ein moralisches Verdienst, wenn sie das Schlechte zurückweist und bewußt das Gute wählt, das sich vom Schlechten abhebt. Insofern ist (...) derjenige, der moralisch richtig handelt, sich anderer Möglichkeiten bewußt. Leibniz trägt dieser Erfahrungstatsache durch den Gedanken Rechnung, daß eine freie Handlung logisch kontingent ist. Diesem Gedanken verleiht Leibniz einen metaphysischen Status: die möglichen Welten haben einen objektiven Gehalt. (shrink)

Cell line immortalisation is a growing component of African genomics research and biobanking. However, little is known about the factors influencing consent to cell line creation and immortalisation in African research settings. We contribute to addressing this gap by exploring three questions in a sample of Xhosa participants recruited for a South African psychiatric genomics study: First, what proportion of participants consented to cell line storage? Second, what were predictors of this consent? Third, what questions were raised by participants during (...) this consent process? 760 Xhose people with schizophrenia and 760 controls were matched to sex, age, level of education and recruitment region. We used descriptive statistics to determine the proportion of participants who consented to cell line creation and immortalization. Logistic regression methods were used to examine the predictors of consent. Reflections from study recruiters were elicited and discussed to identify key questions raised by participants about consent. Approximately 40% of participants consented to cell line storage. The recruiter who sought consent was a strong predictor of participant’s consent. Participants recruited from the South African Eastern Cape, and older participants, were more likely to consent; both these groups were more likely to hold traditional Xhosa values. Neither illness nor education were significant predictors of consent. Key questions raised by participants included two broad themes: clarification of what cell immortalisation means, and issues around individual and community benefit. These findings provide guidance on the proportion of participants likely to consent to cell line immortalisation in genomics research in Africa, and reinforce the important and influential role that study recruiters play during seeking of this consent. Our results reinforce the cultural and contextual factors underpinning consent choices, particularly around sharing and reciprocity. Finally, these results provide support for the growing literature challenging the stigmatizing perception that people with severe mental illness are overly vulnerable as a target group for heath research and specifically genomics studies. (shrink)